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DL-PSMA I&t
DL-PSMA I&t
CAS NO : not yet assigned
Product No : DL-PSMA I&t
Molecular Formula : C63H92IN11O23
Synonyms : (3S,7S,26R,29R,32R)-29-benzyl-32-(4-hydroxy-3-iodobenzyl)-5,13,20,28,31,34-hexaoxo- 37-(4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl)-4,6,12,21,27,30,33-heptaazaheptatriacontane-1,3,7,26,37-pentacarboxylic acid
Application : Precursor for [68Ga/177Lu/90Y] PSMA I&t
- Description
PSMA I&T is a small-molecule ligand that targets prostate-specific membrane antigen (PSMA) with high affinity and is designed for both imaging and therapeutic applications. It can be radiolabeled with isotopes such as 68Ga for PET imaging or 177Lu for targeted radioligand therapy in prostate cancer.
Application: Precursor for [68Ga/177Lu/90Y] PSMA I&tMolecular weight: 1498.37
-Care must be taken when handling this product.
-Do not contact skin or eyes.
-Do not ingest or inhale.
-Store at <-20℃. Protect from light. (Short-term storage (<2 weeks) at higher temperatures (e.g. during transport) does not affect product quality)
-For use by qualified personnel only.
Literature
1.Hunault-Berger, M., Oumata, N., Uzan, G., et al. (2023).
Optimization of 177Lu-Labelling of PSMA I&T and DOTA-TOC for Clinical Application. Pharmaceuticals, 16(2), 265.
2.Nguyen, A., Reesink, P., Albinsson, B., et al. (2025).
Multifactorial Analysis of Radiochemical Purity in High-Activity 177Lu-PSMA I&T and DOTA-TATE Production. EJNMMI Radiopharmacy and Chemistry, 10, Article 12.