CIQM-95【124236-61-9】Precursor for (R,S)-[N-Methyl-11C-]PK11195
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Product Name: (R,S)-N-Desmethyl PK11195
Synonyms: 3-Isoquinolinecarboxamide, 1-(2-chlorophenyl)-N-(1-methylpropyl), -(R,S); 1-(2-Chlorophenyl)-N-(1-methylpropyl)-isoquinoline-3-carboxamide-(R,S)
CAS No.: 124236-61-9
Molecular Formula: C20H19ClN2O
Molecular weight: 338.83
Application: Precursor for (R,S)-[N-Methyl-11C-]PK11195
Presentation: Packaged in amber vial or amber screw cap vials with teflon-coated stoppers under argon atmosphere.

  • Store the product at -20℃ and protected from light. Short term storage at higher temperatures does not affect product quality.

CIQM-95-0010x       10mg per vial
CIQM-95-0020x       20mg per vial
note: x includes A B C and D, A refers to 2ml vial; B refers to 4.5ml vial; C refers to 8ml vial; D refers to 30ml vial
*Customized dispensing is available

  • Camsonne R. et al. Synthesis of N-[11C] methyl, N-(methyl-1-propyl), (chloro-2-phenyl)-1- isoquinoline carboxamide-3 (PK11195): A new ligand for peripheral benzodiazepine receptors. J. Labelled Compd. Radiopharm. 1984, 21, 985-991.

  • Hashimoto K.I. et al. Synthesis and evaluation of 11C-PK11195 for in vivo study of peripheral-type benzodiazepine receptors using positron emission tomography. Ann. Nucl. Med. 1989, 3, 63-71.

  • Shah F. et al. Synthesis of the Enantiomers of [N-methyl-11C]PK 11195 and Comparison of their Behaviours as Radioligands for PK Binding Sites in Rats. Nucl. Med. Biol. 1994, 21, 573-581.

  • Cremer J.E. et al. The Distribution of Radioactivity in Brains of Rats Given [N-methyl- 11C]PK11195 In Vivo After Induction of a Cortical Ischaemic Lesion. Nucl. Med. Biol. 1992, 19, 159-166.