MMSE-95【177714-21-5】Precursor for 16alpha-[18F]Fluoroestradiol
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Product Name: MMSE
Synonyms: Estra-1,3,5(10)-triene-16,17-diol, 3-(methoxymethoxy)-, cyclic sulfate, (16beta,17beta); 3-(Methoxymethoxy)-1,3,5(10)-gonatriene-16beta,17beta diol-16,17-cyclic sulfate; 3-O-(Methoxymethyl)-16,17-O-sulfuryl-16-epiestriol; 3-Methoxymethyl-16beta,17beta- epiestriol-O-cyclic sulfone
CAS No.: 177714-21-5
Molecular Formula: C20H26O6S
Molecular weight: 394.48
Application: Precursor for 16alpha-[18F]Fluoroestradiol
Presentation: Packaged in amber vial or amber screw cap vials with teflon-coated stoppers under argon atmosphere.

  • Store the product at -20℃ and protected from light. Short term storage at higher temperatures does not affect product quality.

MMSE-95-0001x       1mg per vial
MMSE-95-0002x       2mg per vial
MMSE-95-0050x       50mg per vial
MMSE-95-0100x       100mg per vial
note: x includes A B C and D, A refers to 2ml vial; B refers to 4.5ml vial; C refers to 8ml vial; D refers to 30ml vial
*Customized dispensing is available

  • Roemer J. et al. Automated production of n.c.a. 16alpha-[18F]fluoroestradiol. Forschungszent. Rossendorf, [Ber.]FZR 1997, 200, 188-192.

  • Lim J.L. et al. The use of 3-methoxymethyl-16alpha,17beta-epiestriol-O-cyclic sulfone as the precursor in the synthesis of [18F]-16alpha-fluoroestradiol. Nucl. Med. Biol. 1996, 23, 911-915.

  • Roemer J. et al. 13c NMR spectroscopic characterization of estra-1,3,5(10)-triene-3, 17beta-diol and 3,16,17-triols, and some of their 3-O-methoxymethyl and 16alpha-fluoro derivatives. Forschungszent. Rossendort, [Ber.]FZR 1996, 122, 27-30.

  • Berridge M.S. et al. Cyclic sulfates: useful substrates for selective nucleophilic substitution. J. Org. Chem. 1990, 55, 1211-1217.